Gut health: One study demonstrated jujube could provide protection against inflammatory bowel disease, like Crohn’s disease and ulcerative colitis.

The fruit and its seeds are used in Chinese and Korean traditional medicine, where they are believed to alleviate stress, [28] and traditionally for anti-fungal, anti-bacterial, anti-ulcer, anti-inflammatory purposes and sedation, [29] antispastic, antifertility/contraception, hypotensive and antinephritic, cardiotonic, antioxidant, immunostimulant, and wound healing properties. [30] It is among the fruits used in Kampo. Jujube, along with Gan Cao, is used in Chinese medicine to harmonize and moderate other herbs. [ citation needed] In China, jujubes are processed to make wine, which is called hongzaojiu. They use baijiu (Chinese liquor) to preserve jujubes by storing them in a jar. This product maintains its flavor for a long period of time, particularly in winter. Preserved jujubes are called jiuzao. Kurihara, Y. (1992). "Characteristics of antisweet substances, sweet proteins, and sweetness-inducing proteins". Crit Rev Food Sci Nutr. 32 (3): 231–252. doi: 10.1080/10408399209527598. PMID 1418601.

Conflicts of Interest

Apart from medical intervention, you can combat cancerous cells with jujube tea as it carries plant glucosides and saponins, which have the ability to kill cancerous cells by disrupting all cell membranes. It essential combats the bad cells in your body, eliminating tumor growth. 5. Promotes Healthy Digestion Cancer: One group of researchers tested jujube’s effects on human cervical and breast cancer cells. Their results suggest jujube may hold promise in preventing or treating cancer. It’s important to note these studies were conducted in isolated cancer cells (think: Petri dishes, not people).

The hydroalcoholic extract of jujube at 200–400mg/kg was applied onto acute and chronic rat models of inflammation. The study revealed that jujube extract markedly declined granuloma tissue formation, as compared with model rat. Serum nitrite/nitrate level was notably up regulated in inflammatory rat; while pre-treatment with jujube significantly reduced the increased level of nitrite/nitrate ( Goyal et al., 2011). These findings suggest the anti-inflammatory effects of jujube. In line with this, the applied jujube extract at 100–500μg/ml inhibited nitric oxide production and splenocyte proliferation on the inflammatory activated cells ( Yu et al., 2012). The excessive induction of pro-inflammatory cytokines, i.e., IL-1β and IL-6, also contributes to chronic inflammation. In the lipopolysaccharide (LPS)-induced macrophages, the pre-treatment with jujube water extract repressed the expressions of IL-1β and IL-6 ( Chen et al., 2014a). Besides, the triterpene acid fraction of jujube at a dose higher than 10μg/ml was able to inhibit the production TNF-α ( Yu et al., 2012). NF-κB is one of main transcription factors that has vital role in controlling pro-inflammatory cytokine production ( Du et al., 2013). The treatment with jujube extract slightly inhibited NF-κB activity. On the other hand, the pre-treatment with jujube water extract (0–3mg/ml) for 3h in cultured macrophages, before the addition of LPS at 1μg/ml for 24h, dose-dependently repressed the activation of NF-κB activity. The reduction at 60% was observed under the pre-treatment of extract at 3mg/ml ( Chen et al., 2014a). In parallel, the anti-inflammatory property of jujube was shown in colitis-associated colon cancer mice ( Periasamy et al., 2020). In this study, mice were injected with azoxymethane followed by three cycles of dextran sulfate sodium, as to induce colitis-associated colon, before the intake of jujube extract for 70days. The results showed that dietary jujube intake could attenuate inflammation in model mice. Moreover, the extract of jujube markedly inhibited the protein expressions of IL-6, NF-κB, JAK1, and STAT3 in colon tissues, as compared with model group. This result suggests that jujube can suppress the stimulation of NF-κB/IL-6/JAK1/STAT3 signaling ( Periasamy et al., 2020). Jujube in Blood Circulation Phenolic compounds, or phenols, are powerful antioxidants, which means they help fight the effects of free radicals throughout your body.

Results

Evidence-Based Complementary and Alternative Medicine: “A Review of Dietary Ziziphus jujuba Fruit (Jujube): Developing Health Food Supplements for Brain Protection.” According to the previous studies, H 2O 2 is a kind of reactive oxygen species (ROS) produced by stress response in the cells of fruit and vegetable when meet injure, whereas MDA is the main by-product of cell membrane lipid peroxidation in fruits ( 50). Thus, the H 2O 2 and MDA content can reflect the cell membrane permeability, degree of oxidative damage, and fruit aging. Our results showed that short-time CAP treatment could induce seriously the oxidative stress response and increase H 2O 2 content, whereas CAP treatment for a longer time would decrease H 2O 2 content ( Figure 5A). This may be due to longer time exposure can produce more ROS and reactive nitrogen species (RNS), which could effectively lead to serious stress response, so that improve the antioxidant enzyme activities including superoxide dismutase (SOD), catalase (CAT), and ascorbate peroxidase (APX). Rather, short-time treatment could only increase the H 2O 2 content and further damage the cell membrane and other tissues of fruits. Besides, the MDA content in our study was first decreased and then increased with a dynamically change trend ( Figure 5B). This may be due to CAP treatment not only improved the antioxidant enzymes activity, but also inhibited the lipid peroxidase enzyme expression in jujube during storage. Our results were identical to previous studies, which pointed out that dielectric barrier discharge cold plasma treatment for 10 min can inactivate the litchi peroxidase (POD) to 47.16% ( 51). Conclusion Witch's broom, prevalent in China and Korea, is the main disease affecting jujubes, though plantings in North America currently are not affected by any pests or diseases. [15] In Europe, the last several years have seen some 80%–90% of the jujube crop eaten by insect larvae (see picture), including those of the false codling moth, Thaumatotibia (Cryptophlebia) leucotreta. [16]

The research on jujube is preliminary, and its effects haven’t been scientifically tested in people. Let’s see what some of the early research shows and what it may mean.The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supplementary Material Ziziphus jujuba". IUCN Red List of Threatened Species. 2007: e.T63538A12688176. 2007. doi: 10.2305/IUCN.UK.2007.RLTS.T63538A12688176.en . Retrieved 25 April 2021. For antioxidant activity, the results showed that the DPPH scavenging capacity in CAP-treated groups showed no differences as compared to control from days 0 to 10. However, at day 15, the DPPH scavenging capacity of CAP-treated jujubes was decreased as compared to control ( p< 0.05). Moreover, the DPPH scavenging capacity of jujube with or without CAP treatment displays no obvious changes during the 15-day storage. Likewise, the same trend was observed in the ABTS scavenging capacity of jujube at day 0 and 5, which displayed no differences of that in CAP-treated groups as compared to control. Differently, at day 10, the ABTS scavenging capacity of jujube in control was sharply decreased to 59.01%, while of that in CAP5, CAP10, and CAP20 still maintained a high level around 85.00% ( p< 0.05). Phenolic Acid Synthesis-Related Gene Expression

You should aim for 25 to 35 grams of fiber a day. A diet that’s high in fiber has many benefits, including: In addition, jujube was reported to contain numerous minerals, e.g., iron and vitamin. About 0.48mg iron and 69mg vitamin C per 100g of fresh fruit were reported ( Li et al., 2007; USDA, 2012). Thus, the daily intake of jujube could increase our dietary iron and vitamin, as to prevent anemia due to deficiency of iron or vitamin C. Moreover, cAMP was found to have high abundance in jujube, and surprisingly this content was much higher than other horticultural fruits ( Hanabusa et al., 1981). It is well accepted that increasing cAMP level can stimulate protein kinase A and, subsequently, which phosphorylates CREB ( Argyrousi et al., 2020). Besides, jujube cAMP has been found to possess anti-melancholic effect in animal model of depression ( Chi and Zhang, 2009). Thus, it is supposed that the cAMP in the jujube may account for its role on HIF (hypoxia inducible factor)-dependent EPO induction. Jujube on Erythropoiesis They can be eaten raw or dried. And while fresh jujubes aren’t readily available in most parts of the United States, dried jujubes can be found online. Dried versions can be used in recipes similar to other dehydrated fruits. They work well in jams, breads, dessert fillings and more. Or just mix them with nuts to add some chewy bits to your trail mix. Is jujube healthy? The presence of bioactive compounds in jujube prevents your body from falling prey to free radical cell development, which cause symptoms associated with cancer. The antioxidant property of jujube makes it effective in combating cancer and other heart diseases.

Health benefits of Jujube

Laboratory of Plasma Application Technology, Institute of Advanced Technology, University of Science and Technology of China, Hefei, China In Japan, the natsume has given its name to a style of tea caddy used in the Japanese tea ceremony, due to the similar shape. [32] Its hard, oily wood was, along with pear, used for woodcuts to print books starting in the 8th century and continuing through the 19th in China and neighboring countries. As many as 2000 copies could be produced from one jujube woodcut. [33] [ verification needed] Jujube tree is important in Hinduism too as Vishnu is worshipped in a major temple, in Badrinath, from the Sanskrit compound Badarīnātha, consisting of the terms badarī ( jujube tree) and nātha (lord), an epithet of Vishnu. [38] It is also known as Badarikashrama.